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Medications
Targeting specific protein regions offers a new treatment approach in medulloblastoma
Medulloblastoma (the most common malignant childhood brain tumor) is separated into four molecular groups, with Group 3 bearing the worst prognosis. By studying EP300 and CBP, critical proteins in Group 3 medulloblastoma ...
17 minutes ago
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Medical research
Study reports new compound that halts replication of COVID by targeting 'Mac-1' protein in cell models
Research appearing in the Journal of Medicinal Chemistry shows for the first time SARS-CoV-2, the virus responsible for COVID-19, can be inhibited from replicating in living cell cultures using a compound that targets "Mac-1," ...
48 minutes ago
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Medical research news
Shoulder surgeons should rethink a common practice, new study suggests
A common practice of shoulder surgeons may be impairing the success of rotator cuff surgery, a new study from orthopedic scientists and biomedical engineers at Columbia University suggests. The work is published in the journal ...
52 minutes ago
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Study recommends exposing deaf children to sign language before and after cochlear implantation
Many researchers and clinicians advise the parents of a deaf child waiting for a cochlear implant to avoid sign language and focus exclusively on spoken language.
17 minutes ago
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Study reveals racial disparities in COVID-19 testing delays among health care workers
At the height of the pandemic, timely access to COVID-19 testing was crucial for curbing the spread of the disease and informing treatment decisions. Studies have unveiled racial and ethnic disparities in COVID-19 infection ...
46 minutes ago
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Study finds vitamin D alters mouse gut bacteria to give better cancer immunity
Researchers at the Francis Crick Institute, the National Cancer Institute (NCI) of the U.S. National Institutes of Health (NIH) and Aalborg University in Denmark, have found that vitamin D encourages the growth of a type ...
1 hour ago
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Food in sight? The liver is ready in minutes: Study shows how adapting sugar metabolism starts in the brain
What happens in the body when we are hungry and see and smell food? A team of researchers at the Max Planck Institute for Metabolism Research has now been able to show in mice that adaptations in the liver mitochondria take ...
1 hour ago
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Blocking gene may halt growth of breast cancer cells
Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical ...
3 hours ago
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Study finds RNA modification is responsible for disruption of mitochondrial protein synthesis in Alzheimer's disease
A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.
3 hours ago
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Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins ...
3 hours ago
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Using AI to improve diagnosis of rare genetic disorders
Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient using artificial intelligence. The ...
6 hours ago
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Genetic variations may predispose people to Parkinson's disease following long-term pesticide exposure, study finds
A new UCLA Health study has found that certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease.
10 hours ago
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Cancer drug trial provides lessons for future
A cancer drug was found to be ineffective in preventing recurrence of kidney cancer in patients who recently underwent tumor removal surgery, according to a clinical trial published in the Journal of Clinical Oncology.
2 hours ago
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Treatment for deadly superbug C. diff may be weakening
The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research from the University of Houston ...
3 hours ago
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Creatine found to improve cognitive performance during sleep deprivation
Creatine is a popular dietary supplement in the sports community that is used to improve physical performance. Researchers at Forschungszentrum Jülich have now discovered that a high single dose of creatine can temporarily ...
4 hours ago
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Identifying a new liver defender: The role of resident macrophages
Osaka University researchers have discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier ...
5 hours ago
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Researchers create an AI-powered digital imaging system to speed up cancer biopsy results
University of Waterloo researchers have invented a digital medical imaging system that significantly improves the cancer detection process to deliver immediate results and enable swift, effective treatment for all types of ...
5 hours ago
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Link between depression and cardiovascular disease explained: They partly develop from same gene module
Depression and cardiovascular disease (CVD) are serious concerns for public health. Approximately 280 million people worldwide have depression, while 620 million people have CVD.
15 hours ago
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Understanding the cellular mechanisms of obesity-induced inflammation and metabolic dysfunction
A South Korean team has spearheaded a research endeavor that successfully uncovered the mechanisms governing inflammation and metabolic dysfunction in tissues associated with obesity. Their findings were published in Nature ...
6 hours ago
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Researchers publish final results of key clinical trial for gene therapy for sickle cell disease
In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) ...
6 hours ago
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